The Detection of Peroxynitrite Using 19F Magnetic Resonance Probes

Authors

Kevin Bruemmer, Southern Methodist UniversityFollow

Contributor(s)

Dr. Alexander Lippert

Publication Date

Fall 11-23-2014

Abstract

The following report presents the work done by Kevin Bruemmer for his Engaged Learning project. The 19F magnetic resonance probes 5-uoroisatin and 6-uoroisatin were reacted with ONOO- to yield anthranilic acid derivatives through a novel oxidative decarbonyaltion reaction. Utilizing 19F NMR spectroscopy techniques, the presence of ONOO- can be determined through a chemical shift switching signal. 5-uoroisatin was subsequently used to detect ONOO- in living lung epithelial cells.

Document Type

Article

Keywords

Engaged Learning 2014, x-ray detector, silicon PIN diode, circuit

Disciplines

Chemistry

Part of

Engaged Learning

Extent

17 pages

Format

.pdf

Rights

The files in this collection are protected by copyright law. No commercial reproduction or distribution of these files is permitted without the written permission of Southern Methodist University, Cox Business School. These files may be freely used for educational purposes, provided they are not altered in any way, and Southern Methodist University is cited. For more information, contact ncds@smu.edu.

Language

English

Recommended Citation

Bruemmer, Kevin, "The Detection of Peroxynitrite Using 19F Magnetic Resonance Probes" (2014). Collection of Engaged Learning. 63.
https://scholar.smu.edu/upjournal_research/63